Karl Fischer titration applications
Karl Fischer titration, or KF titration, is the tried-and-tested analytical method to determine the amount of water (moisture) in samples. Our application experts have compiled numerous documents on volumetric and coulometric KF titration in various industries, such as food and beverage, pharmaceuticals, or polymers and plastics.
Use the filters to search the Karl Fischer applications by sample matrix, norm, or industry.
- AN-K-074Water content in crude oil determined with Karl Fischer titration
To determine water in crude oil, ASTM D4928 recommends coulometric Karl Fischer titration with the oven method, allowing full automation for high reproducibility.
- AN-K-039Water in penicillin-G-potassium
This application note describes the water content determination in penicillin by using volumetric Karl Fischer titration. Unwanted side reactions can be avoided by using special solvent mixtures.
- AN-K-022Water in pesticide formulations
This Application Note describes the determination of water content in pesticides using Karl Fischer titration.
- AN-K-005Water in ink
Determination of water content in ink is possible with Karl Fischer titration, as shown in this Application Note.
- WP-089Water content determination in ketones using Hydranal™ NEXTGEN FA reagents
With Hydranal™ NEXTGEN FA reagents, the water content in ketones can be determined quickly and reliably. Compared to other existing KF reagents for ketones on the market, the side reactions are measurably better suppressed.
- AN-K-037Water in 2-methyl-5-mercaptothiadiazole
The water content of 2-methyl-5-mercaptothiadiazole is determined according to Karl Fischer using a special solvent mixture to prevent unwanted side reactions.
- AN-K-010Water in coal dust
The water content of coal dust is determined according to Karl Fischer. Because of the low water content of the voluminous sample, the oven method (nitrogen, 270 °C) and coulometric titration have to be used.
- AN-K-006Water in ointments
The water content of ointments is determined according to Karl Fischer. Because of their high water and fat content, the samples are prediluted with a 1:1 mixture of chloroform and methanol.
- AN-K-041Water in liquid ammonia
Determination of the water content of liquid ammonia according to Karl Fischer after absorption of the water in ethylene glycol.
- AN-K-054Determination of the water content in tablets
This Application Note describes the determination of the water content in tablets using automated volumetric titration including sample preparation (MATi 11).
