Karl Fischer titration applications
Karl Fischer titration, or KF titration, is the tried-and-tested analytical method to determine the amount of water (moisture) in samples. Our application experts have compiled numerous documents on volumetric and coulometric KF titration in various industries, such as food and beverage, pharmaceuticals, or polymers and plastics.
Use the filters to search the Karl Fischer applications by sample matrix, norm, or industry.
- AN-K-074Water content in crude oil determined with Karl Fischer titration
To determine water in crude oil, ASTM D4928 recommends coulometric Karl Fischer titration with the oven method, allowing full automation for high reproducibility.
- AN-K-053Determination of the water content in toothpaste with MATi 10
This Application Note describes the automated determination of the water content in toothpaste using volumetric Karl Fischer titration (MATi 10).
- AN-K-052Determination of the water content in sodium acetate with MATi 10
In this application note, Karl Fischer titration is used to determine water content in sodium acetate trihydrate. The MATi 10 allows this determination to be automated, saving users time in the laboratory.
- AN-K-051Determination of the water content in spirits with MATi 10
This Application Note describes the automated determination of the water content in liqueur (30% v/v) using volumetric Karl Fischer titration (MATi 10).
- AN-K-039Water in penicillin-G-potassium
This application note describes the water content determination in penicillin by using volumetric Karl Fischer titration. Unwanted side reactions can be avoided by using special solvent mixtures.
- AN-K-038Water in N-acetyl-L-cysteine
Karl Fischer titration can be used to determine the water content in N-acetyl-L-cysteine. Special solvent mixtures can be used to prevent unwanted side reactions in the Karl Fischer titration. The water content of N-acetyl-L-cysteine can thus be determined quickly and accurately, as is shown in this Application Note.
- AN-K-019Water in urea
In this application note, Karl Fischer titration is used to determine the water content of urea.
- AN-K-022Water in pesticide formulations
This Application Note describes the determination of water content in pesticides using Karl Fischer titration.
- AN-K-005Water in ink
Determination of water content in ink is possible with Karl Fischer titration, as shown in this Application Note.
- AN-K-068Water content determination and acid-base titration in parallel
The water content determination by volumetric Karl Fischer titration is one of the most important analyses worldwide. Using an OMNIS system consisting of an OMNIS Titrator and an OMNIS Sample Robot, the fully automatic analysis of water content is possible in various products and matrices. The OMNIS Sample Robot is capable of running several different titrations in parallel. In this Application Note, we present the results of a volumetric Karl Fischer titration run in parallel to an aqueous acid-base titration on the same system. The water content is not influenced by the parallel running aqueous titration, allowing the combination of potentiometric titrations and Karl Fischer titrations on the same automated system.
