A cardioplegic solution protects the ischemic myocardium from cell death. It is applied together with hypothermia e.g. in open heart surgery. Here the simultaneous determination of aspartic acid, glutamic acid, tris(aminomethyl)aminomethane (TRIS), sodium and potassium in such a solution is given. The two amino acids can be determined as they are partially in the triple protonated ammonium form at the eluent pH. Determination is achieved by direct conductivity detection.

Whey is the remaining liquid after cheese production. It is mainly used as feed. It is also used as dietary supplement as a beverage or in powder form. This application determines lactic acid as well as cations in one determination. The Metrosep C 6 - 250/4.0 column separates sodium, potassium, magnesium, and calcium by ion exchange. It also acts as an ion-exclusion column, which separates lactic acid. Both lactic acid and the cations can be determined in the same run applying direct conductivity detection. While cations typically elute as negative peaks, lactic acid elutes as an early positive peak. MagIC Net shows both in the usual positive direction.

Bicine (2-(Bis(2-hydroxyethyl)amino)acetic acid) is a corrosive component. It has to be avoided in acidic gas sweetening solvents. These solvents are based on organic amines. Bicine is amphoteric, holding a carboxylic and an amine group. Under the applied conditions, the amine groups are at least partially protonated and therefore may be separated by cation chromatography. The detection mode is direct conductivity detection.

Within the scope of the USP monograph modernization, potassium is determined in potassium bitartrate applying cation chromatography with direct conductivity detection. The USP41 monograph for “Potassium bitartrate” does not yet mention an assay for potassium. The separation is performed on a Metrosep C 6 - 150/4.0 column (L76). The assay of potassium is performed with two commercially available products according to USP definitions. All acceptance criteria are fulfilled.

Within the scope of the USP monograph modernization, potassium is determined in potassium sodium tartrate applying cation chromatography with direct conductivity detection. The USP41 monograph for “Potassium sodium tartrate” does not yet mention an assay for potassium. The separation is performed on a Metrosep C 6 - 150/4.0 column (L76). The assay of potassium is performed with two commercially available products according to USP definitions. All acceptance criteria are fulfilled.

Within the scope of the USP monograph modernization, potassium is determined in potassium bicarbonate effervescent tablets for oral suspension applying cation chromatography with direct conductivity detection. The separation is performed on a Metrosep C 6 - 150/4.0 column (L76). All acceptance criteria are fulfilled.

As an alternative to flame photometry, ion chromatography with non-suppressed conductivity detection has been approved by the USP as a validated method to quantify potassium and sodium content in potassium and sodium bicarbonates and citric acid effervescent tablets for oral solution. The present IC method has been validated according to USP General Chapter <621>.

As an alternative to flame photometry, ion chromatography with non-suppressed conductivity detection has been approved by the USP as a validated method to quantify potassium content in potassium bicarbonate and potassium chloride effervescent tablets for oral solution. The Metrosep C 6 - 150/4.0 column (L76) provides the required separation of potassium and magnesium. The present IC method has been validated according to USP General Chapter <621>.

Within the scope of the USP monograph modernization, sodium is determined in potassium sodium tartrate applying cation chromatography with direct conductivity detection. The USP41 monograph for «Potassium sodium tartrate» does not yet mention an assay for sodium. The separation is performed on a Metrosep C 6 - 150/4.0 column (L76). The assay of potassium is performed with two commercially available products according to USP definitions. All acceptance criteria are fulfilled. See AN-C-182 for the respective determination of potassium. Apllying this method allows to determine sodium and potassium simultaneously according to USP.

Natural liquefied petroleum gas (LPG) is a mixture of hydrocarbon gases (e.g. propane and butane), but it also contains acidic contaminants (e.g. carbon dioxide or hydrogen sulfide). These gases need to be scrubbed from the petroleum gas as they are highly corrosive. This purification step, referred to as «sweetening», is often performed by using alkaline amine solutions. Thereby the amine solution absorbs the acidic gases, while the raw LPG is neutralized. To guarantee that amine residues in the sweetened gas do not influence the gas quality, the amines in the final LPG are determined by scrubbing the gas with acetic acid as described in UOP 936-96. The recent method enables the quantification of the amines dimethylamine (DMA), diethylamine (DEA), dipropylamine (DPA), and dibutylamine (DBA) by separation from standard cations.