Stool analysis in under one minute

The reference laboratory in France for biochemical exploration of stools and exploration of intestinal homeostasis was looking for a faster analysis method that would limit the need for solvents and sample preparation. Near-infrared spectroscopy (NIR spectroscopy) and the NIRS DS2500 Solid Analyzer from Metrohm proved to be a viable solution.

We choose Metrohm because this company is both the supplier and the manufacturer allowing a direct support by the company for the development and validation processes.

Dr. Laurence Barbot-Trystram,

Medical biologist, Ph.D. pharmacist at University Hospital Pitié Salpêtrière - Charles Foix, France

NIR spectroscopy to the rescue

The functional coprology lab of the university is in charge of analyzing lipids, nitrogen, carbohydrates, energy, bacterial metabolites, electrolytes, calprotectin, and elastase in stool samples. They turned to NIR spectroscopy because of the following advantages:

Fast and hygienic measurements
No solvents and sample preparation needed
Automation options
Multiparameter analysis (lipids, nitrogen, and hydration can be analyzed at the same time in one measurement)

In the beginning, they faced some challenges with other NIRS analyzers not from Metrohm, as the results were not satisfactory. After close collaboration between Metrohm and the laboratory team, the methods for even the difficult samples (e.g., very liquid or greasy samples) could be validated and a reliable NIRS analyzer was in place.

Fast, robust, and user-friendly NIR analyzer

The NIRS DS2500 Solid Analyzer from Metrohm is used in two areas:

A routine sector that groups the main biological analyses performed for exploration of diarrhea (nutrients, electrolytes, and metabolites measurements)
A specialized sector dedicated to nutritional assessments and follow-up of patients who have undergone digestive surgery such as extensive intestinal resection leading to malabsorption and wasting conditions leading to intestinal failure, by-pass, or intestinal transplantation

According to the laboratory, the advantages of the NIRS DS2500 Solid Analyzer can be summarized as follows:

Time-saving with regards to sample preparation, measurement, and analyzer maintenance
Reduced turnaround time for results
User-friendly software, also for people without laboratory experience
Non-destructive analysis

Among all the NIRS analyzers, the DS2500 analyzer is the best suited to fecal samples.

Dr. Laurence Barbot-Trystram,

Medical biologist, Ph.D. pharmacist at University Hospital Pitié Salpêtrière - Charles Foix, France

Mentioned products

DS2500 Solid Analyzer

2.922.0010

Robust near-infrared spectroscopy for quality control, not only in laboratories but also in production environments.The DS2500 Analyzer is the tried and tested, flexible solution for routine analysis of solids, creams, and optionally also liquids along the entire production chain. Its robust design makes the DS2500 Analyzer resistant to dust, moisture, vibrations, and temperature fluctuations, which means that it is eminently suited for use in harsh production environments.The DS2500 covers the full spectral range from 400 to 2500 nm and delivers accurate, reproducible results in less than one minute. The DS2500 Analyzer meets the demands of the pharmaceutical industry and supports users in their day-to-day routine tasks thanks to its simple operation.Thanks to accessories tailored perfectly to the instrument, optimum results are achieved with every sample type, no matter how challenging it is, e.g. coarse-grained solids such as granulates or semi-solid samples such as creams. The MultiSample Cup can help improve productivity when measuring solids, as it enables automated measurements of series containing up to 9 samples.

NIRS reflection standard, set of 2

6.7450.000

Set of wavelength standard and 80% reflection standard for the calibration of an NIRS XDS MasterLab Analyzer, NIRS XDS RCA Analyzer, NIRS XDS MultiVial Analyzer, NIRS XDS SmartProbe Analyzer, NIRS XDS Interactance OptiProbe Analyzer and NIRS DS2500 Analyzer.

Vision Air 2.0

6.6072.201

Vision Air - Universal spectroscopy softwareVision Air is a modern and simple-to-operate software solution.Overview of the advantages of Vision Air: Individual software applications with adapted user interfaces ensure intuitive and simple operation; Simple creation and maintenance of operating procedures; SQL database for safe and simple data management; The Vision Air version (66072201) contains the following applications: Application for instrument and data management; Application for routine analysis; Select this version when you already have a software for method development (Vision, PLS_Toolbox or Unscrambler®).

Pre-calibration for human feces

6.6072.314

Pre-calibration for the determination of the dry mass of the fat content, the nitrogen content, the water content, and the calorie content using NIR spectroscopy

2 / 4

Additional information:

Brochure: Pre-calibration for the analysis of human stool

Interview: Stool analysis with NIR Spectroscopy

Application note: Human stool analysis by near-infrared spectroscopy

More customer voices View all customer voices

Polymer ID verification in under two minutes

Hauff-Technik relies on the handheld Raman spectrometer MIRA XTR from Metrohm for fast and reliable ID verification of incoming polymer pellets.

Automated analysis of water

The Laboratory of the Swiss Canton of Zurich uses OMNIS and TitrIC from Metrohm for fast, reliable, and reproducible drinking water analyses.

Europe's largest shrimp farm – in Switzerland!

SwissShrimp monitors the seawater quality using an automated ion chromatography system from Metrohm.