Applications

The Combustion IC system presented allows the automated determination of organic halogen and sulfur compounds in all flammable samples. Both combustion digestion, which is automatically controlled with a flame sensor, and the professional Liquid Handling guarantee highest precision and trueness. This poster describes the determination of the halogen and sulfur content in a certified polymer standard, a coal reference material as well as in latex and vinyl gloves.

Determination of traces of ammonium in the presence of sodium, potassium, magnesium, and calcium using cation chromatography with direct conductivity detection.

The determination of halogens and sulfur in waste products is important. The inline combination of the Mitsubishi Combustion Module with the Metrohm IC is a suitable method for this type of samples. The recovery rates are analyzed with a certified reference material, e.g., a low-density polyethylene (LDPE).Keyword: pyrohydrolysis

Combustion Ion Chromatography combines pro-hydrolytic sample combustion and the absorption of emerging combustion gases in an oxidizing, aqueous solution that is then channeled to an ion chromatograph for the analysis of halogenides and sulfur (as sulfate). The combustion and analysis of the certified reference materials (ZRM) makes clear the reliability of Metrohm Combustion Ion Chromatography.Keyword: pyrohydrolysis

This Application Note looks at the determination of fluorine and sulfur in certified liquefied gas using Metrohm Combustion IC. Sequential determinations proceed in parallel to a certain extent: While the absorption solution of a sample that has already been combusted is being analyzed with IC, the combustion of the next sample is already underway.Keyword: pyrohydrolysis

In the application note AN-EIS-004 on equivalent circuit models, an overview of the different circuit elements that are used to build an equivalent circuit model was given. After identifying a suitable model for the system under investigation, the next step in the data analysis is estimation of the model parameters. This is done by the non-linear regression of the model to the data. Most impedance systems come with a data-fitting program. In this application note, the way NOVA is uses to fit the data is shown.

The water content determination by volumetric Karl Fischer titration is one of the most important analyses worldwide. Using an OMNIS system consisting of an OMNIS Titrator and an OMNIS Sample Robot, the fully automatic analysis of water content is possible in various products and matrices. The OMNIS Sample Robot is capable of running several different titrations in parallel. In this Application Note, we present the results of a volumetric Karl Fischer titration run in parallel to an aqueous acid-base titration on the same system. The water content is not influenced by the parallel running aqueous titration, allowing the combination of potentiometric titrations and Karl Fischer titrations on the same automated system.

Karl Fischer reagents contain buffer substances (usually imidazole) since the reaction constant is dependent on the pH value. A constant pH therefore ensures the most repeatable results. In 2015, imidazole was classified by European Union the as a CMR (carcinogenic, mutagenic or toxic) substance and the statement H360D was added, stating possible harm to fertility or a fetus. Meanwhile, other reagents free of imidazole are available for purchase. This Application Note summarizes test measurements with 34433 HYDRANAL™ NEXTGEN Coulomat AG-FI.

This Application Note describes how the accuracy of your NIR measurements can be increased with instrument calibration.

This Application Note describes how the accuracy of your NIR measurements can be increased with reference standards.

The automated combination of pyrolysis and subsequent ion chromatography (Combustion IC) permits the parallel detection of halogens and sulfur in all flammable solid and liquid matrices. The method is captivating, not only because of its outstanding precision and trueness, but also because of the high sample throughput.

Combustion IC (CIC) stands for the automated combination of combustion digestion and ion chromatography. In a single analysis step, the CIC enables the parallel detection of halogens and sulfur in complex matrices. The method requires neither a separate method development for combustion nor an internal standard for quantification.

This white paper summarizes the steps involved in converting an existing manual titration procedure to semi-automated or automated titration procedures. It discusses topics such as selecting the right electrode and titration mode. For a better understanding, the discussion topics are illustrated with three examples.

The objective of validation of an analytical procedure is to demonstrate that it is suitable for its intended purpose. Recommendations for the validation of analytical methods can be found in ICH Guidance Q2(R1) Validation of Analytical Procedures: Text and Methodology and in USP General Chapter <1225> Validation of Compendial Procedures. The goal of this white paper is to provide some recommendations for the validation of titration methods.